Tickseed are wildflowers that need consistently moist soils with little drought tolerance. Poorly drained soils can also pose problems for these perennials as rots can occur. Deadheading spent flowers can promote new fall blooms and prevent propagation via self seeding. Deadheading can be done by picking off individual flower heads or shearing the entire plant. Shearing will also help to keep the foliage tidy. They may spread by creeping roots that occasionally sprout a new plant. If left unchecked, they can become invasive groundcovers.
There are few serious disease or insect issues that plague Tickseed. Rots can occur in poorly drained soils. Scorch and scarce flowering may occur in dry and hot conditions. The foliage and stems may become matted in areas exposed to heat, humidity, and heavy summer rainfalls. These perennials prefer cool summer climates.